Gallery

Scientific Gallery

Light-activated Corelet droplets made from BRD4's IDR (green) form and dissolve within the chromatin (H2B, magenta) of a U2OS cell nucleus

BRD4 Corelets showing larger condensates in relaxed chromatin regions, smaller in dense chromatin regions.

H2B-marked chromatin showing exclusion of chromatin from condensates, and relaxation of chromatin after deactivation.

Targeted light activation can trigger droplet formation in spatiotemporally controlled manner <3

FUS condensates (green) nucleate and grow at FUS-marked telomeres (magenta). Upon deactivation, droplet dissolution brings two telomeres together, repositioning them in the nucleus.

BRD4 condensates nucleate repeatedly at sites of genomic acetylation

Upon JQ1 treatment, the same nucleus shows significantly different BRD4 condensate nucleation, growth and diffusion behaviors.

Cajal bodies (magenta) marked with FUS-coilin spread onto the surface of FUS Corelet droplets (green). Fusion of coilin-ringed FUS droplets leads to repositioning of the original cajal bodies.

Scientific illustrations

Strom et al Nature 2017

Strom & Brangwynne JCS 2019

Patil*, Strom* et al Cell 2023

Strom*, Kim*, et al Cell 2024

Out and about

Celebrating one year of Strom Group at the Dog Surfing Championships, Aug 2026

Setting up Strom Lab
at Genentech, Aug 2025

Brangwynne lab retreat 2024

Princeton coffee run, 2020

Blavatnik Ceremony 2024

Amy was honored by the Blavatnik Foundation as a Finalist for their Regional Postdoc Award in 2024. See highlights of the Gala, held on October 1 in the Natural History Muesum, in this youtube video (left).